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See how our purpose-driven Environmental, Social and Governance (ESG) strategies empower and drive us.View our commitmentWe strive for a culture where our employees are connected to our purpose, provided with a breadth of career opportunities, and can bring their authentic selves to work.Explore our cultureLearn about our dedication to the pursuit of scientific and technological innovation to develop alternatives to animals in testing.Explore New Approach MethodologiesAt Charles River, we are driven to partner with Disruptors fighting every day to unlock the secrets of the brain.Meet the DisruptorsEureka's Sounds of ScienceView AllBlog PostPCR-based screening: A Solid 3Rs Choice During QuarantineYour Guide to IND-Enabling Study NeedsMeeting on the Med and Mesa: Post Event CGT ResourcesAdvancing CAR-T Therapy with PDX ModelsAdvancing Rapid Microbial Detection with Celsis®Join our teamView allApr 17 - 22, 2026 | San Diego, CA | Cancer Research Annual Meeting 2026Interphex 2026Managing Aquatic Colonies: Navigating Different WatersHSPA Annual Conference 2026Bioassays Symposium 2026Explore the PortfolioResearch Models and Services Support your basic research with help from the leading global supplier of laboratory animal models and services.Human Immune and Stem Cells The leading developers of cutting-edge cell therapies and basic research trust us as their cell sourcing provider.Genetically Engineered Animals and Services Genetically Engineered Animal Models and Services (GEMS) team helps you select, customize, and maintain the right mice for your research. Services for genetically engineered animals include mouse and rat model creation, breeding, genotyping, and mouse embryo and sperm cryopreservation.Discover the OfferingsIntegrated Drug Discovery Reduce time to clinic by up to a year with an integrated drug discovery approach in which target discovery, hit id, hit-to-lead, lead optimization, safety, and toxicology are all managed by the same project team.Discovery Pharmacology Studies In vitro to in vivo translation is difficult, costly, and often fails. Advance your discovery research with our translationally focused approach across a range of therapeutic areas including oncology, neuroscience, and immunology.Antibody Discovery Services Antibody discovery services designed with your IND in mind. Comprehensive solutions, tailored to your unique vision for your next antibody therapeutic.Learn What’s PossibleNon-GLP Integrated Toxicology Two primary study offerings are available for non-GLP toxicology studies for lead optimization and preclinical development.IND-enabling Programs Successfully initiate and complete your IND-enabling program while meeting regulatory expectations with our unique range of IND-enabling studies.Carcinogenicity Studies Our carcinogenicity studies include expert support in project design, model selection, and in vivo and ex vivo data for final submission.Find Out MoreBiologics Testing Solutions Our tailored global testing and manufacturing services support clients throughout the biologic development cycle, from discovery through preclinical and clinical studies to marketed product release.Biologics Contract Manufacturing Accelerate the development of your biopharmaceutical from concept to cure with our CGMP compliant biologics contract manufacturing services. RightsourceSM – Biologics Insourcing Solutions A flexible testing platform that can be deployed where and when you need it, whether it’s located at your facility, one of our satellite labs, or even within the walls of the many Charles River facilities itself.Get the DetailsCell and Gene CDMO Solutions Fastrack your cell and gene development and manufacturing with our end-to-end scalable solutions from early stage-research and testing through commercial release.Biologics Testing and Manufacturing Solutions Navigate seamlessly throughout the biologic development cycle, from early concept to market-ready with our tailored, CGMP global testing and manufacturing solutions.Microbiology Quality Control Solutions Elevate your contamination control strategy and accelerate production with confidence. Our rapid, accurate, and compliant microbial testing solutions optimize your QC workflow.Meet the ExpertsOne Step Manufacturing One Step by Charles River is a comprehensive, tailored suite of CRO drug discovery and development services in target discovery, lead optimization, development chemistry, GMP, drug product development and CMC strategy.Fast Lane Expedite your investigational new drug (IND) application with Fast Lane Paradigm. Learn how to reduce white space between studies and accelerate time to clinic for you INDs.IND-Enabling Studies Toolbox Charles River can conduct an investigational new drug (IND) study from start to finish, and offers stand-alone studies needed for IND-enabling submissions. Our IND experts have expertise in all major therapeutic areas, including medical devices and gene and cell therapies.

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